内皮抑素的表达与直肠癌侵袭行为的关系
2页1、文章来源 毕业论文网 内皮抑素的表达与直肠癌侵袭行为的关系文章来源 毕业论文网 Relationship between endostatin expressionand the invasion of rectal cancerABSTRACT: Objective To investigate the relation of endostatin (ES) and the vascular formation in rectal cancer, and the effect of ES on the invasion of rectal cancer. Methods The expression level of ES and microvessel density (MVD) in 10 cases of normal rectal tissues and 40 cases of rectal cancer were detected by immunohistochemistry staining. Results The express
2、ion level of ES in normal rectal tissues was obviously stronger than that in rectal cancer (P<0.05). There was a negative relation between the expression level of ES and MVD in rectal cancer with the changes of the depth of infiltration and lymph node metastasis (P<0.05). Conclusion With the decrease of ES, the number of knubbly vessels increases. The decrease of ES can promote infiltration of rectal cancer and metastasis of lymph node.KEY WORDS: endostatin; microvessel density; rect
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