质子碳离子加速器.ppt

IBA Carbon therapy system PTCOG 47, JAX, May 2008 Yves Jongen IBA sa,A cyclotron for Carbon therapy? Are you crazy?,In 1991, when IBA entered in PT, the consensus was that the best accelerator for PT was a synchrotron IBA introduced a very effective cyclotron design, and today the majority of PT centers use the cyclotron technology (Not only IBA but Accel/Varian, Still Rivers) Over these 15 years, users came to appreciate the advantages of cyclotrons: Simplicity & reliability Intense, continuous (non pulsed) beam current Lowest cost and size But, most importantly, the ability to modulate rapidly and accurately the proton beam current,In less space and cost than a synchrotron: a two cyclotrons phased approach,,One cyclotron IBA proton-carbon therapy system,The IBA Carbon cyclotron design,Superconducting isochronous cyclotron, accelerating all Q/M = 1/2 ions to 400 MeV/U (Alphas, Lithium, Boron, Carbon, but also Nitrogen, 0xygen, Neon and Argon 36 for research) Accelerates also protons as H2+. Protons are extracted by stripping around 270 MeV Design similar to IBA PT cyclotron, but with higher magnetic field thanks to superconducting coils, and increased diameter (6.3 m vs. 4.7 m) Treatment field 20 x 20 cm. Scanning beam only.,Change of energy?,Cyclotrons are simpler at fixed energy Energy change by graphite degrader at waist after cyclotron exit, followed by divergence slits and energy analyzer Fragmentation products are effectively eliminated in slits and ESS Yes, neutrons are produced, but ESS is well shielded and the average beam current in PT or CT is very low > little activation How fast? 5 mm step in energy in 100 msec at PSI (vs. 5 msec for Cyclinac). But respiration cycle is 2…4 seconds, so 100 msec is fine,Status of the cyclotron,During the last three years, a team of accelerator physicists at the JINR in Dubna has completed the physical design of the cyclotron. This study has been summarized into a comprehensive design report. On January 8th 2007, an international design review was organized by IBA, with worlds key superconducting cyclotron experts. The outcome of the review was completely positive. Construction of the prototype has started A design contest has just been organized between the SC coils suppliers. Results were reviewed. Contract negotiated with Sigmaphi + CERN consultants.,Status of the IBA carbon system in April 08,In the competition for contracts, the lack of a carbon cyclotron prototype is a significant weakness For this reason, the board of IBA decided the construction of a prototype on IBA budget, and the installation of the prototype at a scientific partner to validate the system by the end of 2011 The scientific partner is now selected. It is the scientific laboratories association Archade associated with the GANIL national laboratory (Caen, France),The agreement signed in February 2008,IBA will, at his own cost, install the C400 prototype in Caen, close to the GANIL laboratory, within the frame of a research project with ARCHADE. Within the frame of this research project, the region will, at his own cost, finance the building and electricity. Archade will hire, and IBA will pay 9 to12 scientists to work on radiobiology and hadron therapy related physics issues to contribute to a carbon TPS. The goal is to establish a center of resources and knowledge in hadron therapy, and to validate the IBA system, treating a first patient in 2011. The goal is not to create a clinical therapy center (Lyon’s Etoile project comes first),A Proton/Carbon therapy TPS,IBA has launched an international collaboration for the development of a better, biologically optimized treatment planning system for carbon beams, to be included into an existing, commercial TPS Participants to the collaboration include: The INFN (Italy) Dresden University/ Oncoray (Prof. M. Bauman) The ARCHADE collaboration (Prof. J. Bourhis) Industrial partners (IBA, CMS-Elekta),Compact isocentric gantry for Carbon beams,MD’s want a true isocentric gantry The gantry of Heidelberg (20 m long, 12 m diameter, 600 Tons) is often seen as too large, heavy and expensive to be selected as a solution Is it possible to build a Carbon gantry of the size and (more or less) the cost of a proton gantry? Yes, if the last dipole magnet is superconductive (3.2 T) and if scanning is done upstream of this last dipole,The compact carbon gantry,,Superconducting 90° magnet,40° magnet,40° magnet,Scanning magnet,Patient positioner,Superconducting dipole magnet cross section,1 - Coldmass assembly 2 - Mulitlayer insulation 3 - Liquid N2 cooled shield 4 - Mulitlayer insulation 5 - Coldmass vacuum tank 6 - G10 support tube assembly 7 - 80 K heat sink (copper) 8 - Bellows 9 - Preload cartridge 10 - Anchor cartridge 11 - Magnet support quadrant 12 - Magnet support tie plate 13 - Vacuum tank preload protuberance 14 - Vacuum tank anchor protuberance 15 - Liquid He supply tube 16 - He vapor return tube,+,,Thank you…,。