完整word版NMR常见溶剂峰和水峰.docx

溶剂1卜化学位移8（精细多重峰数）JHD/Hz13C化学位移8（精细多重峰数）JCD/HzNM瞎剂中残余H2gHOD勺质子化学移相对密度（20C）熔点/c沸点/C丙酮一d62.05(5)2.2206.68(13)29.92(7)0.919.42.80.87-9457氯仿-d7.27(1)77.23(3)32.01.51.50-6462重水4.80(DSS)4.81(TSP)4.81.113.8101.4N,N-二甲基甲酰胺-dy8.03(1)2.92(5)2.75(51.91.9163.15(3)34.89(7)29.76(729.421.021.13.51.04-61153二甲基亚砚-d62.50(5)1.939.51(7)21.03.31.1818189甲醇-d44.87(1)3.31(5)1.749.15(7)21.44.90.89-9865注：JHD为溶剂本身的其他1H对与之相对应的1H之间的耦合常数，JCD为溶剂本身1H对13C的耦合常数，H2C^交换了D的HO耻的1H产生的即水峰的化学位移氯仿：小、中小、中等极性DMSO芳香系统（日光下自然显色、紫外荧光）对于酚羟基能够出峰。

芳香化合物还是芳香忒，都为首选毗嚏：极性大的，特别是皂忒对低、中极性的样品，最常采用觉代氯仿作溶剂，因其价格远低于其它觉代试剂极性大的化合物可采用觉代丙酮、重水等针对一些特殊的样品，可采用相应的觉代试剂：如觉代苯（用于芳香化合物、芳香高聚物）、觉代二甲基亚砚（用于某些在一般溶剂中难溶的物质）、觉代毗嚏（用于难溶的酸性或芳香化合物）等丙酮：中等极性甲醇：极性大氯仿一甲醇：石：乙5;1小极性石：丙2:1——1:1中等极性氯仿：甲醇6:1极性以上含有一个糖2:1含有两个糖含有糖的三茹皂忒：一般用毗嚏常见溶剂的1H在不同免代溶剂中的化学位移值mult.笊代溶剂CDCl3(CD3)2CO(CD3)2SOC6D6CD3CNCD3ODD2OC5D5N7.20残余溶剂峰7.262.052.507.161.943.314.797.578.72水峰brs1.562.843.330.402.134.874.794.96CHC13s7.268.028.326.157.587.90(CH3)2COs2.172.092.091.552.082.152.22(CH3)2SOs2.622.522.541.682.502.652.71CeH6s7.367.367.377.157.377.33CH3CNs2.102.052.071.551.962.032.06CH3OHCH,sOH,s3.491.093.313.123.164.013.073.282.163.343.34CH⑵,m8.628.588.588.538.578.538.528.72C5H5NCH(3),m7.297.357.396.667.337.447.457.20CH(4),m7.687.767.796.987.737.857.877.57CH3,s2.051.971.991.651.972.012.07CH3COOC2H5CH2,q4.124.054.033.894.064.094.14CH3,t1.261.201.170.921.201.241.24CH2CI2s5.305.635.764.275.445.49n-hexaneCH3,tCH2,m0.881.260.881.280.861.250.891.240.891.280.901.29C2H5OHCH3,tCH2,q1.253.721.123.571.063.440.963.341.123.541.193.601.173.65常见溶剂的13C在不同笊代溶剂中的化学位移值M代溶剂CDCI363)28(CD3)2SOC6D6CD3CNCD3ODD2OC5D5N123.44溶剂峰77.16206.2639.52128.061.3249.00-135.4329.84118.26149.84CHC1377.3679.1979.1677.7979.1779.44(CH3)2CO207.07205.87206.31204.43207.43209.67215.9430.9230.6030.5630.1430.9130.6730.89(CH3)2SO40.7641.2340.4540.0341.3140.4539.39CeHe128.37129.15128.30128.62129.32129.34116.43117.60117.91116.02118.26118.06119.68CH3CN1.891.121.030.20仍0.851.47CH3OH50.4149.7748.5949.9749.9049.8649.50149.90150.67149.58150.27150.76150.07149.18C5H5N123.75124.57123.84123.58127.76125.53125.12135.96136.56136.05135.28136.89138.35138.2721.0420.8320.6820.5621.1620.8821.15171.36170.96170.31170.44171.68172.89175.26CH3COOC2H560.4960.5659.7460.2160.9861.5062.3214.1914.5014.4014.1914.5414.4913.92CH2CI253.5254.9554.8453.4655.3254.7814.1414.3413.8814.3214.4314.45n-hexane22.7023.2822.0523.0423.4023.6831.6432.3030.9531.9632.3632.73核磁知识(NMR)一：样品量的选择氢谱，氟谱，碳谱至少需要5mg.1H-1HCOSY,1H-1HNOESY,1H-13CHMBC,1H-13CHSQC需要10-15mg.碳谱需要30mg.二：如何选择觉代溶剂常用觉代溶剂：CDC13,DMSO,D2O,CD3OD.特殊觉代溶剂：CD3COCD3,C6D6,CD3CN。

极性较大的化合物可以选择用D2O或CD3OD，如果想要观察活泼氢切记不能选择D2O和CD3ODCDCl3为人民币2-3元，D2O为人民币6元，DMSO为人民币10元，CD3OD为人民币30元Solvent化学位移(PPm)水峰位移(ppm)CDCl37.261.56DMSO2.503.33CD3OD3.314.87D2O4.79CD3COCD32.052.84。