药剂学英文术语.docx

生物药剂学英文汉译英要求Biopharmaceutics 生物药剂学Absorption 吸收Distribution 分布 Metabolism 代谢Excretion 排泄Transport 转运Disposition 处置 Elimination 消除Transcellular pathway 细胞通道转运 Paracellular pathway 细胞旁路通道转运 Passive transport 被动转运Pore transport 膜孔转运Carrier-mediated transport 载体媒介转运 Facilitated diffusion 易化扩散、促进扩散 Active transport 主动转运Membrane mobile transport 膜动转运 Pinocytosis 胞饮作用Phagocytosis 吞噬作用First pass effect 首过效应pH-partition hypothesis pH-分配假说 Dissolution 溶出Parenteral drug delivery 注射给药Oral cavity mucosa drug delivery 口腔粘膜给药 Transdermal drug delivery 皮肤给药 Nasal mucosa drug delivery 鼻粘膜给药 Pulmonary drug delivery 肺部给药 Rectal drug delivery 直肠给药 Ophthalmic drug delivery 眼部给药 Distribution 分布Accumulation 蓄积Apparent volume of distribution 表观分布容积 Metabolize, metabolism 代谢 Biotransformation 生物转化Inhibition 酶抑制作用 Inhibitor 酶抑制剂Induction 酶诱导作用 Inducer 酶诱导剂英译汉要求Membrane transport 膜转运Fluid mosaic model 生物膜液态镶嵌模型 Extrinsic proteins 外在蛋白Intrinsic proteins 内在蛋白Fluidity 流动性Asymmetry 不对称性 Semipermeability 半透性P-glycoprotein P 糖蛋白Vesicle 小泡Endocytosis 入胞作用Exocytosis 出胞作用 Kerckring 环状褶壁 Villi 绒毛Epithelium cell 上皮细胞Microvilli 微绒毛Apical membrane 顶侧膜Brush border membrane 刷状缘膜Basal membrane 基底膜 Lateral membrane 侧细胞膜Tight junction 紧密结合Solvent drag effect 溶媒牵引效应 Gastric emptying rate 胃空速率 Liver first pass effect 肝首过效应 Lymphatic circulation 淋巴循环 Ionization 解离度Lipophilicity 脂溶性Dissolution rate 溶出速率 Molecular weight 分子量Oil-water partition coefficient 油水分配系数 Sink condition 漏槽条件Critical particle size, CPS 临界粒径 Polymorphism 多晶型Absorption number, An 吸收指数 Dose number, Do 剂量指数Dissolution number, Dn 溶出指数 Permeation enhancer 透过促进剂或 Absorption enhancer 吸收促进剂 Solid dispersion tech 固体分散技术 Dispersible tablet 分散片 Effervescent tablet 泡腾片 Sustained-release preparation 缓释制剂 Controlled-release preparation 控释制剂Stability 稳定性Day/night rhythm 昼夜节律Site-specific drug delivery system 定位释药系统Oral delayed-release preparation 口服迟释制剂Stomach-specific preparation 口服胃滞留制剂Floating 漂浮型Swelling 膨胀型Sticking 粘附型Intestine-specific preparation 小肠迟释制剂Oral colon-specific drug delivery system, OCDDS 口服结肠定位给药系统 In vitro experimental model 离体实验模型Tissue flux chambers 组织流动室法Mucosa 粘膜Secosa 浆膜Everted gut sac 外翻肠囊法Everted rings 外翻环法In situ experimental model 原位实验模型Intestine perfusion method 肠道灌流法In vivo experimental model 体内法Intravenous injection 静脉注射Intramuscular injection 肌内注射Hypodermic injection 皮下注射Intradermic injection 皮内注射Solid particle precipitation 固体粒子析出Masticatory mucosa 咀嚼粘膜Lining mucosa 内衬粘膜Specialized mucosa 特性粘膜Buccal mucosa 颊粘膜Sublingual mucosa 舌下粘膜Transdermal drug delivery system, TDDS/Transdermal therapeutic system 经皮给药 系统Physiologic factors 生理因素Iontophoresis 离子导入技术Cilia movement 纤毛运动Surfactant 表面活性剂Eyelid 眼睑Eye adjunct 眼附属器Cornea 角膜Drug-protein binding 药物-蛋白结合Albumin 白蛋白Alpha acid glycopro tein, AAG酸性糖 蛋白Lipoprotein 脂蛋白Binding constant 结合常数Blood-brain barrier 血- 脑脊液屏障Inter-membrane transfer 膜间转运Contact release 接触释放Adsorption 吸附Fusion 融合Endocytosis 内吞Pinocytosis 胞饮Long-circulating DDS 长循环微粒给药系统Target drug delivery system 靶向给药系统Intracellular target of biomacromolecule 生物技术药物的细胞内靶向Liver microsome enzymes 微粒体药物代谢酶系Live microsome mixed function monooxygenase 肝微粒体混合功能氧化酶或单加 氧酶Glucuronyl transferase 葡萄糖醛酸转移酶The first phase reaction 第一相反应Combination reaction 结合反应Optical isomerism 光学异构Cortex 皮质Medulla 髓质Nephron 肾单位Glomerular filtration 肾小球滤过Active tubular secretion 肾小管分泌Tubular reabsorption 肾小管重吸收Inulin 菊粉Biliary excretion 胆汁排泄Renal clearance 肾清除率Enterohepatic cycle 肠肝循环Compartment model 隔室模型Single compartment mode 一室模型Two compartment model 二室模型Multicompartment model 多室模型First order processes 一级速度过程Zero order processes 零级速度过程Nonlinear processes 非线性速度过程Pharmacokinetics, PK 药物动力学Population pharmacokinetics, PPK 群体药物动力学Clinical pharmacokinetics 临床药物动力学 Therapeutic drug monitoring, TDM 治疗药物监测 Chronopharmacokinetics 时辰药物动力学Physiological pharmacokinetic model 生理药物动力学模型Biological half life 生物半衰期Sigma-minus method 亏量法，又称总和-减量法Steady-state drug concentration 稳态血药浓度Loading dose 负荷剂量Lag time 滞后时间Extravascular delivery 血管外给药Plateau level 坪浓度 Fluctuation percentage, FI 波动百分数 Degree of fluctuation, DF 波动度 Product inhibition 产物抑制Plasma drug concentration change percentage 血药浓度变化率 Capacity-limited process 容量限制过程Design of dosage regimen 临床给药方案设计 Individualization of drug dosage regimes 给药方案个体化 Bioavailability 生物利用度Extent of bioavailability, EBA 生物利用程度 Rate of bioavailability, RBA 生物利用速度 Absolute bioavailability, Fabs 绝对生物利用度 Relative bioavailability, Frel 相对生物利用度 Pharmaceutical equivalence 药剂等效性 Bioequivalence 生物等效性。