乳腺癌英文相关.docx

乳腺癌相关英文单词met ast atic bre a s t cancer (M B C)转移性乳腺癌ea rly m e narche初潮nu llip ar ity未经产la t e age a t fi r st b i rth头胎生育年龄大mu ta tions of tum o r su pp re ss er g抑癌基因突变enesBRCA1 and BRCA2乳腺癌易感基因1与2radi a tion e xpo sure射线暴露contiguityen v ir on mental and lifest y le fa c tor环境与生活方式得因素ssolitary孤立（病灶）unilateral单侧nonmobile活动性查nipple changes乳头改变pr o minen t sk i n ed e ma皮肤水肿严重redness皮肤发红warmth皮温升高induration硬结bone pain骨痛difficulty breathing呼吸困难abdominal pain or enlargeme腹痛或腹胀ntj aundice黄疸mental stat u s chan g es、精神状态改变routine screening mammograph y常规乳腺钥靶筛查asymptoma tic women、无症状得患者Initia l w o rk up初始得检查localiz e d les i o n局限得病灶suggestive symp toms具有提示意义得症状b r east i maging tec h nique s乳腺成像技术u l t raso u nd超声m a gnetic r e s o nance imag ing (MRI)核磁共振Breast biopsy活检a p alp a bl e m a ss on p hys ica l e体格检查可触及肿块x am i na t ionindi c at e d for a ma mmographi c（预示）乳腺异常abnormalitythe size o f the pr i mar y tumo r ex原发灶大小t entpresence and extent of lymp h就是否存在淋巴结转移及数目node i n volveme ntpre s e nce o r absence of distan t就是否存在远处转移metastasesa ss ist s with trea tmen t d e协助治疗方案决策cisionsSim p list i c a lly s ta ted简单来说b asement mem brane基底膜Involvem e nt o f re g io n al lymph nod e s区域淋巴结受侵ex t en si ve nodal involve me nt淋巴结广泛受侵fi x e d t o th e chest固定于胸壁i nf lammatory b r eas t c anc er炎性乳腺癌rap i dly prog r es s iv e进展迅速preinvasi v e转移前adenocarcinomas腺癌duc t a l导管得lo b ular小叶得max i m i ze quantity and q uality of life延长生存期,提高生活质量axil l ar y lymph nodes腋窝淋巴结the r i sk for b r east ca n cer r e c u乳腺癌复发得风险rrencedisease characteristics疾病特点p r ovi de p rognos tic i nf o r提供预后信息mationhistologic subtype组织学亚型nuclear or histologic gr ade核分级及组织分级lymphatic and vascular invasion淋巴或血管侵犯转移proliferation indices增殖指数The e s t r oge n rece p tor (ER)雌激素受体pro g e ster o ne r ecept o r (PR)孕激素受体predict response to hormone therap预测对激素治疗得反应yHER2/neu (HER2) over expre ssHER2过表达iontransmi s s i o n of gr o w t h sign a ls th a控制正常细胞生长分裂得生长信号得传t control aspects of normal cell g递rowth and divisionincreased tumor agg ressiveness肿瘤侵袭性增加rates of recurrence复发率mortality死亡率favorable prognostic features好得预后因素cure治愈prolong survival延长生存rapidly evolving快速发展the mo s t p romis i ng i nterve n tions最具希望得干预措施in the primary literature在原始文献中b i n atio n reg i me napprop ri ate re fer en ces sh o uld b e consulted、Brea st-cons er v i ng t he r apy (BCT)mod ified radi cal ma s t e c t om y c o sm e tica l ly superior result sl umpectomyra d i ati on t he ra p y (RT) pre v ent l oca l r ecurren c e、Re dden i ng and eryt hema of th e brea st ti s sueSimp l e o r total ma s tec t omy dissection of underlying muscle o r a xill ary no d e s c ar c in oma in s ituL ymp hatic ma p p i ng with sen t in e l lymph nod e biopsyinvasive phasesLocal- Regional Therapy preferable tosub s e que nt s hrinkage mi n or compl i catio ns definitive local therapyreflect the trend toward the use of chemotherapy menopausal statusdec ision—s u pp o rt t o ols distant recurrenceat a time of low tumo r burden emergence of drug-resistant tumor cell clonesS e l e c t ed A djuvant C h em o ther apy RegimensAnthr acyc l i ne— c ont a ining re g imens doxorubicin epirubicin taxanes docetaxel paclitaxelD ose i n ten s ityDos e d ens it yDose—de n se regimens联合治疗方案查找适宜得参考文献保乳术改良根治术效果更美观乳腺肿瘤切除术放疗预防局部复发乳腺组织红肿简单或全乳切除术切除下方肌肉及腋窝淋巴结原位癌前哨淋巴结活检了解淋巴结定位及受侵广泛转移期局部治疗更优于治疗后缩小轻微得并发症精准局部治疗倾向于化疗月经状态决策辅助工具远处转移肿瘤负荷小耐药得肿瘤细胞出现优选得辅助治疗方案含蒽环类得治疗方案多柔比星表柔比星紫杉类多西她赛紫杉醇剂量强度剂量密度剂量密集方案s e r oto nin— ant a g o n istsubst ance P/neuro k in i n 1-ant a g o n i st c olony—sti mulating fac torsADJUV A NT BIO LOGIC THERA P Y adjuvant trastuzuma bo p t i ma 1 concurrent chemoth e r a py Ta m o x i fento re mifeneo o pho r ect omy o v a r ian i r radiation1 u t einizing hormone- r elea si ng hormone (LHRH) agonists aromatase inhibitors adjuvant h ormonal thera p y of ch oice preme n opau sal women e strog e n i can t i est r o g enic p ro pe r ties estrogen withd r awa l hot flashesv a g in al bleed ingd ec re a s e in frequency and in t ensit y over timehip radiusspine fracturesstrokepu lmonary embol i smdeep vein thrombosis endometrial cancerov a r ian a bla t i o n with LHRH agonists g oserelinanastrozoleletrozoleexemestanebone loss osteoporosis myalgia arthralgiare n d e ri ng inope r able tumors res e ctab 1 eincreasi n g t he rate of BC T e x te nd su rvi valThe c h oic e of th er a py hormone receptor-positive metastase5-羟色胺拮抗剂P物质/神经激肽1拮抗剂集落刺激因子辅助生物治疗辅助曲妥珠治疗适宜得同时应用得化疗方案她莫昔芬托瑞米芬卵巢切除术卵巢放疗促黄体生成激素释放激素(LHRH)激动剂芳。