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分子生物学-特纳第二版课后练习题(最新整理)
9页1、Section C - properties of nucleic acids1. The sequence 5-AGTCTGACT-3 in DNA is equivalent to which sequence in RNA?A 5-AGUCUGUGACU -3B 5 -UGTCTGUTC -3C 5 -UCAGUCUGA-3D 5- AGUCAGACU-32. Which of the following correctly describes A-DNA?A a right-handed antiparallel double helix with 10 bp/turn and bases lying perpendicular tothehelix axis.B a left-handed antiparallel double-helix with 12 bp/turn formed fromalternating pyrimidine-purinesequences.C a right-handed antiparallel double helix with 11 bp
2、/turn and bases tilted with respect to the helix axis.D a globular structure formed by short intramolecular helices formed in a single-strand nucleic acid.3. Denaturation of double stranded DNA involves. Abreakage into short double-stranded fragments.B separation into single strands.C hydrolysis of the DNA backbone.D cleavage of the bases from the sugar-phosphate backbone.4. Which has the highest absorption per unit mass at a wavelength of 260 nm? Adouble-stranded DNA.B mononucleotides.C RNA.D p
3、rotein.5. Type I DNA topoisomeraes . A change linking number by 士 2 B require ATP.C break one strand of a DNA double helix.D are the target of antibacterial drugs.Section D - Prokaryotic and eukaryotic chromatin structure1Which of the following is common to both E. coli and eukaryotic chromosomes? Athe DNA is circular.B the DNA is packaged into nucleosomes.C the DNA is contained in the nucleus.1D the DNA is negatively supercoiled.2A complex of 166 bp of DNA with the histone octamer plus histone
4、HI is known as a . . .A nucleosome core.B solenoid.C 30 nm fiber.D chromatosome.3. In what region of the interphase chromosome does transcription take place? Athe telomere.B the centromere.C euchromatin.D heterochromatin.4. Which statement about CpG islands and methylation is not true? ACpG islands are particularly resistant to DNase I.B CpG methylation is responsible for the mutation of CpG to TpG in eukaryotes.C CpG islands occur around the promoters of active genes.D CpG methylation is associ
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