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矮小双语讲座.ppt

19页
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    • Short Stature2021/8/121 Short stature Aim and claim1.Understanding the growth of infant and child2.Familiar with the causes of short stature (mainly get hold of the causes of endocrine disorders)3.Get hold of the examination and investigation of short stature4. Get hold of the management of short stature2021/8/122 The growth of infant and child2021/8/123 Short StaturelAs growth is the essential biological characteristic of childhood,failure of physical growth may be an important sign of disease.lShort stature occurs in several endocrine diseases as the hormones from the pituitary,thyroid,adrenals and gonads are involved in growth.lOther types of disease in childhood can also impair growth and so the differential diagnosis of the short child is wide2021/8/124 Short StaturelThere is a rapidly decelerating growth phase in infancy dependent on nutritionlThe steady,slowly decelerating growth phase in childhood is dependent on growth hormonelThe rapidly accelerating and decelerating pubertal growth spurt is dependent upon the normal secretion of GH and sex steroids2021/8/125 Three periods1、 infancy the first year 25cm the second year 10cm the third year 7cm2、 childhood 5~7cm per year3、 adolescence:boys 25~28cm girls 25cm 45~50%32~40%15~18%2021/8/126 DefinitionslAny child whose height falls below the 3rd centile for his or her community should be considered short.lThe mean heights of children vary with race,geography.2021/8/127 2021/8/128 2021/8/129 Causes of short stature *Endocrine disorders: A.growth hormone deficiency B.hypopituitarism C.hypothyroidism D.Cushing syndrome*Familial short stature*Constitutional delay of pubertal growth spurt*lowbirth weight ;malnutrition*Chromosomal disorders/syndrome:A.Turner syndromeB.Silver-Russell syndrome *Skeletal dysplasias: achondroplasia*Emotional/psychosocial deprivation dwarfism*Chronic illness:A.congenital heart diseaseB.cystic fibrosisC.cerebral palsyD.chronic renal failure 2021/8/1210 p9、 人的价值,在招收诱惑的一瞬间被决定。

      2024/9/11 2024/9/11 Wednesday, September 11, 2024p10、低头要有勇气,抬头要有低气2024/9/11 2024/9/11 2024/9/11 9/11/2024 10:07:48 AMp11、人总是珍惜为得到2024/9/11 2024/9/11 2024/9/11 Sep-24 11-Sep-24p12、人乱于心,不宽余请2024/9/11 2024/9/11 2024/9/11 Wednesday, September 11, 2024p13、生气是拿别人做错的事来惩罚自己2024/9/11 2024/9/11 2024/9/11 2024/9/11 9/11/2024p14、抱最大的希望,作最大的努力11 九月 20242024/9/11 2024/9/11 2024/9/11p15、一个人炫耀什么,说明他内心缺少什么九月 242024/9/11 2024/9/11 2024/9/11 9/11/2024p16、业余生活要有意义,不要越轨2024/9/11 2024/9/11 11 September 2024p17、一个人即使已登上顶峰,也仍要自强不息。

      2024/9/11 2024/9/11 2024/9/11 2024/9/112021/8/1211 烦恼有何惧怕,既然躲不掉,就调好心态与它共存心向阳光,何惧风霜茫茫人海你我相遇就是缘分,欢迎下载!2021/8/1212 Growth hormone deficiency(GHD)lGH is produced by the anterior pituitary gland under the stimulation of GHRH and GHRIHlGH is secreted in a pulsatile pattern in rsponse to sleep,exercise,and hypoglycemia etc 2021/8/1213 GHDlDecreased growth velocitylDelay in skeletal maturation,and subnomal GH secretionlMaybe isolated or with other pituitary hormone deficiencies2021/8/1214 GHDlIdiopathic GHD congenital, genetic(gene mutation) dyspituitarismlAcquired GHD histiocytosis,cranial irradiation,etclTemporary GHD Constitutional delay of pubertal growth spurt hypothyroidism2021/8/1215 GHDlInfants GHD are of normal birth weight, slightly reduced in lengthlExcess truncal adiposityl Normal intellect lNormal body proportions2021/8/1216 2021/8/1217 Growth hormone deficiencylPatients who are significantly short or are growing slowly,in whom GH insufficiency is considered.lIf the preliminary GH level is low ,formal provocative testing by insulin-induced hypoglycaemia,L-dopa or clonidine or more complex is indicated so that patients with classical severe GH deficiency may be identified.2021/8/1218 p9、 人的价值,在招收诱惑的一瞬间被决定。

      2024/9/11 2024/9/11 Wednesday, September 11, 2024p10、低头要有勇气,抬头要有低气2024/9/11 2024/9/11 2024/9/11 9/11/2024 10:07:49 AMp11、人总是珍惜为得到2024/9/11 2024/9/11 2024/9/11 Sep-24 11-Sep-24p12、人乱于心,不宽余请2024/9/11 2024/9/11 2024/9/11 Wednesday, September 11, 2024p13、生气是拿别人做错的事来惩罚自己2024/9/11 2024/9/11 2024/9/11 2024/9/11 9/11/2024p14、抱最大的希望,作最大的努力11 九月 20242024/9/11 2024/9/11 2024/9/11p15、一个人炫耀什么,说明他内心缺少什么九月 242024/9/11 2024/9/11 2024/9/11 9/11/2024p16、业余生活要有意义,不要越轨2024/9/11 2024/9/11 11 September 2024p17、一个人即使已登上顶峰,也仍要自强不息。

      2024/9/11 2024/9/11 2024/9/11 2024/9/11谢谢大家谢谢大家2021/8/1219 。

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