医学英语-皮肤系统skin#
35页1、The skin and Skin Regenerative Medicine再生医学Lujun Yang Burns and Plastic suregery Center for Translational medicine2nd Hospital of Shantou UniversityKayi Name?Aging skinskin the largest organ in the body protect sense regulate temperature Production of Vitamin DClininiansDermatology-dermatologist Plastic and esthetic surgery-plastic surgeonKeratinocyte fibroblastOBJECTIVEMaster skinskin structure and functionepidermisepidermis-keratinization 角化作用 :proliferation增殖/differentiation分化Acquaitance Anom
2、alies异常现象 of skin- common skin diseases Advance Skin regenerative medicine皮肤再生医学INTRODUCTIONepidermisdermishypodermisDermis真皮Papillary layer乳头层+Reticular layer网状层第二节真皮epidermishypodermisdermisskindermis 真皮papillary layer 乳头层 reticular layer 网织层appendages 附属器hair 毛 sebaceous gland 皮脂腺 sweat gland 汗腺 THE STRUCTURE OF SKINepidermis 表皮stratum corneum 角质层stratum lucidum (透明层)stratum granulosum 颗粒层stratum spinosum 棘层stratum basale 基底层nail 指(趾)甲 EPIDERMIS主要细胞组成 keratinocytekeratinocyte(角质形成细胞 ) non-non
3、-keratinocytekeratinocyte(非角质形成细胞) differentiationstratum corneum角质层stratum granulosum颗粒层stratum lucidum(透明层)stratificationstratum basale基底层stratum spinosum棘层(一)Epidermal stratification and differentiationPSORIASIS 银屑病red and white hues of scaly patches appearing on the top first layer of the epidermis (skin). Langerhans cell (郞格汉斯细胞)Langerhans cells are dendritic cells (antigen- presenting immune cells) of the skin and mucosa, and contain large granules called Birbeck granules. They are present
4、 in all layers of the epidermis, but are most prominent in the stratum spinosum. In skin infections, the local Langerhans cells take up and process microbial antigens to become fully functional antigen-presenting cells.Langerhans cells derive from the cellular differentiation of monocytes with the marker “Gr-1“ (also known as “Ly-6G/Ly-6C“). This differentiation requires stimulation by colony stimulating factor (CSF)-1.6 They are similar in morphology and function to macrophages.Albinos lack an
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